Department Publications 2011

Akk G, Li P, Bracamontes J, Wang M, Steinbach JH. Pharmacology of structural changes at the GABA(A) receptor transmitter binding site. Br J Pharmacol 2011;162:840-50.

Akk G, Steinbach JH. Structural studies of the actions of anesthetic drugs on the gamma-aminobutyric acid type A receptor. Anesthesiology 2011;115:1338-48.

Al-Hasani R, Bruchas MR. Molecular mechanisms of opioid receptor-dependent signaling and behavior. Anesthesiology 2011;115:1363-81.

Asaad BO, Helwani M, Wheeler DM, O'Connor MS. Use of non-partitioned ventilator tubing results in dead-space ventilation hypercarbia. Respir Care 2011;56:698-701.

AuBuchon J, Krucylak C, Murray DJ. Subglottic airway foreign body: a near miss. Anesthesiology 2011;115:1300.

Avidan MS, Evers AS. Review of clinical evidence for persistent cognitive decline or incident dementia attributable to surgery or general anesthesia. J Alzheimers Dis 2011;24:201-16.

Avidan MS, Jacobsohn E, Glick D, Burnside BA, Zhang L, Villafranca A, Karl L, Kamal S, Torres B, O'Connor M, Evers AS, Gradwohl S, Lin N, Palanca BJ, Mashour GA. Prevention of intraoperative awareness in a high-risk surgical population. N Engl J Med 2011;365:591-600.

Avidan MS, Kheterpal S. Perioperative mortality in developed and developing countries. Lancet 2012;380:1038-9.

Avidan MS, Mashour GA. Prevention of Intraoperative Awareness with Explicit Recall: Making Sense of the Evidence. Anesthesiology 2013;118:449-56.

Avidan MS, Smith JR, Skrupky LP, Hill L, Jacobsohn E, Burnside B, Tymkew H, Eby C, Damiano R, Despotis GJ. The occurrence of antibodies to heparin-platelet factor 4 in cardiac and thoracic surgical patients receiving desirudin or heparin for postoperative venous thrombosis prophylaxis. Thromb Res 2011;128:524-9.

Baikoussis NG, Apostolakis EE, Katsanos K, Koletsis EN, Karanikolas M, Dougenis D. Huge expanding extrapleural haematoma in a coronary artery disease patient: conservative or surgical treatment? Eur Rev Med Pharmacol Sci 2011;15:978-9.

Baysinger CL, Pope JE, Lockhart EM, Mercaldo ND. The management of accidental dural puncture and postdural puncture headache: a North American survey. J Clin Anesth 2011;23:349-60.

Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michan S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J. Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling. Proc Natl Acad Sci U S A 2011;108:E952-61.

Bloom J, Hinrichs AL, Wang JC, von Weymarn LB, Kharasch ED, Bierut LJ, Goate A, Murphy SE. The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans. Pharmacogenet Genomics 2011;21:403-16.

Boomer JS, To K, Chang KC, Takasu O, Osborne DF, Walton AH, Bricker TL, Jarman SD, 2nd, Kreisel D, Krupnick AS, Srivastava A, Swanson PE, Green JM, Hotchkiss RS. Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA 2011;306:2594-605.

Bottros MM, Palanca BJ, Mashour GA, Patel A, Butler C, Taylor A, Lin N, Avidan MS. Estimation of the bispectral index by anesthesiologists: an inverse turing test. Anesthesiology 2011;114:1093-101.

Bracamontes J, McCollum M, Esch C, Li P, Ann J, Steinbach JH, Akk G. Occupation of either site for the neurosteroid allopregnanolone potentiates the opening of the GABAA receptor induced from either transmitter binding site. Mol Pharmacol 2011;80:79-86.

Bracamontes JR, Li P, Akk G, Steinbach JH. A neurosteroid potentiation site can be moved among GABAA receptor subunits. J Physiol 2012;590:5739-47.

Brown SM, Holtzman M, Kim T, Kharasch ED. Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active. Anesthesiology 2011;115:1251-60.

Bruchas MR, Schindler AG, Shankar H, Messinger DI, Miyatake M, Land BB, Lemos JC, Hagan CE, Neumaier JF, Quintana A, Palmiter RD, Chavkin C. Selective p38alpha MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction. Neuron 2011;71:498-511.

Burykin A, Peck T, Krejci V, Vannucci A, Kangrga I, Buchman TG. Toward optimal display of physiologic status in critical care: I. Recreating bedside displays from archived physiologic data. J Crit Care 2011;26:105 e1-9.

Caldwell CC, Hotchkiss RS. The first step in utilizing immune-modulating therapies: immune status determination. Crit Care 2011;15:108.

Chen DL, Zhou D, Chu W, Herrbrich P, Engle JT, Griffin E, Jones LA, Rothfuss JM, Geraci M, Hotchkiss RS, Mach RH. Radiolabeled isatin binding to caspase-3 activation induced by anti-Fas antibody. Nucl Med Biol 2012;39:137-44.

Cho JH, Saini DK, Karunarathne WK, Kalyanaraman V, Gautam N. Alteration of Golgi structure in senescent cells and its regulation by a G protein gamma subunit. Cell Signal 2011;23:785-93.

Christo PJ, Manchikanti L, Ruan X, Bottros M, Hansen H, Solanki DR, Jordan AE, Colson J. Urine drug testing in chronic pain. Pain Physician 2011;14:123-43.

Culverhouse RC, Saccone NL, Stitzel JA, Wang JC, Steinbach JH, Goate AM, Schwantes-An TH, Grucza RA, Stevens VL, Bierut LJ. Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. Hum Genet 2011;129:177-88.

Dallas J, Brown SM, Hock K, Scott MG, Skrupky LP, Boyle WA, 3rd, Kollef MH. Diagnostic utility of plasma procalcitonin for nosocomial pneumonia in the intensive care unit setting. Respir Care 2011;56:412-9.

Dallas J, Skrupky L, Abebe N, Boyle WA, 3rd, Kollef MH. Ventilator-associated tracheobronchitis in a mixed surgical and medical ICU population. Chest 2011;139:513-8.

Evers AS, Owens WD. Memories and dreams: building an academic department at Washington University in St. Louis. Anesthesiology 2011;115:1147-8.

Evers AS, Van Aken H. Congratulations from the IARS! Anesthesiology 2011;115:679-80.

Fan J, Brown SM, Tu Z, Kharasch ED. Chemical and enzyme-assisted syntheses of norbuprenorphine-3-beta-D-glucuronide. Bioconjug Chem 2011;22:752-8.

Fan J, Meissner K, Gaehle GG, Li S, Kharasch ED, Mach RH, Tu Z. Automated radiosynthesis of [11C]morphine for clinical investigation. Appl Radiat Isot 2011;69:431-5.

Fehr JJ, Boulet JR, Waldrop WB, Snider R, Brockel M, Murray DJ. Simulation-based assessment of pediatric anesthesia skills. Anesthesiology 2011;115:1308-15.

Fingerman M. Regional anesthesia for outpatient hand surgery: ultrasound-guided peripheral nerve block. J Hand Surg Am 2011;36:532-4; quiz 4.

Fuller BM, Gajera M, Schorr C, Gerber D, Dellinger RP, Zanotti S. The association of prior statin use in septic shock treated with early goal directed therapy. Eur J Emerg Med 2011.

Garg R, Sunder RA. Valproate-induced hyperammonemia and seizures: perioperative concerns. Paediatr Anaesth 2011;21:1084-5.

Gazit AZ, Fehr J. Perioperative management of the pediatric cardiac transplantation patient. Curr Treat Options Cardiovasc Med 2011;13:425-43.

Graetz TJ, Tellor BR, Smith JR, Avidan MS. Desirudin: a review of the pharmacology and clinical application for the prevention of deep vein thrombosis. Expert Rev Cardiovasc Ther 2011;9:1101-9.

Hinrichs AL, Murphy SE, Wang JC, Saccone S, Saccone N, Steinbach JH, Goate A, Stevens VL, Bierut LJ. Common polymorphisms in FMO1 are associated with nicotine dependence. Pharmacogenet Genomics 2011;21:397-402.

Hu HJ, Gereau RWt. Metabotropic glutamate receptor 5 regulates excitability and Kv4.2-containing K channels primarily in excitatory neurons of the spinal dorsal horn. J Neurophysiol 2011;105:3010-21.

Inoue S, Bo L, Bian J, Unsinger J, Chang K, Hotchkiss RS. Dose-dependent effect of anti-CTLA-4 on survival in sepsis. Shock 2011;36:38-44.

Jeffry J, Kim S, Chen ZF. Itch signaling in the nervous system. Physiology (Bethesda) 2011;26:286-92.

Jin X, Steinbach JH. A portable site: a binding element for 17beta-estradiol can be placed on any subunit of a nicotinic alpha4beta2 receptor. J Neurosci 2011;31:5045-54.

Karanikolas M, Aretha D, Tsolakis I, Monantera G, Kiekkas P, Papadoulas S, Swarm RA, Filos KS. Optimized perioperative analgesia reduces chronic phantom limb pain intensity, prevalence, and frequency: a prospective, randomized, clinical trial. Anesthesiology 2011;114:1144-54.

Kavsak PA, Walsh M, Srinathan S, Thorlacius L, Buse GL, Botto F, Pettit S, McQueen MJ, Hill SA, Thomas S, Mrkobrada M, Alonso-Coello P, Berwanger O, Biccard BM, Cembrowski G, Chan MT, Chow CK, de Miguel A, Garcia M, Graham MM, Jacka MJ, Kueh JH, Li SC, Lit LC, Martinez-Bru C, Naidoo P, Nagele P, Pearse RM, Rodseth RN, Sessler DI, Sigamani A, Szczeklik W, Tiboni M, Villar JC, Wang CY, Xavier D, Devereaux PJ. High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study. Clin Biochem 2011;44:1021-4.

Kertai MD, Pal N, Palanca BJ, Lin N, Searleman SA, Zhang L, Burnside BA, Finkel KJ, Avidan MS. Association of perioperative risk factors and cumulative duration of low bispectral index with intermediate-term mortality after cardiac surgery in the B-Unaware Trial. Anesthesiology 2010;112:1116-27.

Kertai MD, Palanca BJ, Pal N, Burnside BA, Zhang L, Sadiq F, Finkel KJ, Avidan MS. Bispectral index monitoring, duration of bispectral index below 45, patient risk factors, and intermediate-term mortality after noncardiac surgery in the B-Unaware Trial. Anesthesiology 2011;114:545-56.

Kharasch ED. Intraoperative methadone: rediscovery, reappraisal, and reinvigoration? Anesth Analg 2011;112:13-6.

Kharasch ED, Francis A, London A, Frey K, Kim T, Blood J. Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimal and noninvasive probes for hepatic and first-pass CYP3A induction. Clin Pharmacol Ther 2011;90:100-8.

Kharasch ED, Vangveravong S, Buck N, London A, Kim T, Blood J, Mach RH. Concurrent assessment of hepatic and intestinal cytochrome P450 3A activities using deuterated alfentanil. Clin Pharmacol Ther 2011;89:562-70.

Kiekkas P, Karga M, Lemonidou C, Aretha D, Karanikolas M. Medication errors in critically ill adults: a review of direct observation evidence. Am J Crit Care 2011;20:36-44.

Kim T, London A, Kharasch ED. Simultaneous determination of alfentanil and midazolam in human plasma using liquid chromatography and tandem mass spectrometry. J Pharm Biomed Anal 2011;55:487-93.

Kirby BJ, Collier AC, Kharasch ED, Whittington D, Thummel KE, Unadkat JD. Complex drug interactions of HIV protease inhibitors 1: inactivation, induction, and inhibition of cytochrome P450 3A by ritonavir or nelfinavir. Drug Metab Dispos 2011;39:1070-8.

Koniari I, Mavrilas D, Papadaki H, Karanikolas M, Mandellou M, Papalois A, Koletsis E, Dougenis D, Apostolakis E. Structural and biomechanical alterations in rabbit thoracic aortas are associated with the progression of atherosclerosis. Lipids Health Dis 2011;10:125.

Lai HH, Qiu CS, Crock LW, Morales ME, Ness TJ, Gereau RWt. Activation of spinal extracellular signal-regulated kinases (ERK) 1/2 is associated with the development of visceral hyperalgesia of the bladder. Pain 2011;152:2117-24.

Lakshminarasimhachar A, Wildes TS, Pal N, Graetz TJ. Lung transplantation on extracorporeal membrane oxygenation with iatrogenic aortic dissection. J Cardiothorac Vasc Anesth 2011;25:1121-4.

Leighton BL, Wall MH, Lockhart EM, Phillips LE, Zatta AJ. Use of recombinant factor VIIa in patients with amniotic fluid embolism: a systematic review of case reports. Anesthesiology 2011;115:1201-8.

Leuthardt EC, Lim CC, Shah MN, Evans JA, Rich KM, Dacey RG, Tempelhoff R, Chicoine MR. Use of movable high-field-strength intraoperative magnetic resonance imaging with awake craniotomies for resection of gliomas: preliminary experience. Neurosurgery 2011;69:194-205; discussion -6.

Li P, Ann J, Akk G. Activation and modulation of human alpha4beta2 nicotinic acetylcholine receptors by the neonicotinoids clothianidin and imidacloprid. J Neurosci Res 2011;89:1295-301.

Li P, McCollum M, Bracamontes J, Steinbach JH, Akk G. Functional characterization of the alpha5(Asn398) variant associated with risk for nicotine dependence in the alpha3beta4alpha5 nicotinic receptor. Mol Pharmacol 2011;80:818-27.

Liu XY, Liu ZC, Sun YG, Ross M, Kim S, Tsai FF, Li QF, Jeffry J, Kim JY, Loh HH, Chen ZF. Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids. Cell 2011;147:447-58.

Liu Y, Jiang Y, Si Y, Kim JY, Chen ZF, Rao Y. Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice. Nature 2011;472:95-9.

Mashour GA, Avidan MS. Pharmacologic approaches to the prevention of intraoperative awareness. Expert Rev Neurother 2011;11:611-3.

Mashour GA, Orser BA, Avidan MS. Intraoperative awareness: from neurobiology to clinical practice. Anesthesiology 2011;114:1218-33.

McBride ME, Waldrop WB, Fehr JJ, Boulet JR, Murray DJ. Simulation in pediatrics: the reliability and validity of a multiscenario assessment. Pediatrics 2011;128:335-43.

McGreevy K, Bottros MM, Raja SN. Preventing Chronic Pain following Acute Pain: Risk Factors, Preventive Strategies, and their Efficacy. Eur J Pain Suppl 2011;5:365-72.

Mohr NM, Fuller BM, Skrupky LP, Moy H, Alunday R, Micek ST, Fagley RE. Clinical and demographic factors associated with antipyretic use in gram-negative severe sepsis and septic shock. Ann Pharmacother 2011;45:1207-16.

Mohr NM, Hotchkiss RS, Micek ST, Durrani S, Fuller BM. Change in temperature profile may precede fever and be an early indicator of sepsis: a case report. Shock 2011;36:318-20; discussion 20-1.

Montana MC, Conrardy BA, Cavallone LF, Kolber BJ, Rao LK, Greco SC, Gereau RWt. Metabotropic glutamate receptor 5 antagonism with fenobam: examination of analgesic tolerance and side effect profile in mice. Anesthesiology 2011;115:1239-50.

Morrissey JJ, London AN, Lambert MC, Kharasch ED. Sensitivity and specificity of urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 for the diagnosis of renal cell carcinoma. Am J Nephrol 2011;34:391-8.

Murray DJ. Current trends in simulation training in anesthesia: a review. Minerva Anestesiol 2011;77:528-33.

Nagele P. Augmented CPR: rescue after the ResQ trial. Lancet 2011;377:276-8.

Nagele P. Perioperative genomics. Best Pract Res Clin Anaesthesiol 2011;25:549-55.

Nagele P, Liggett SB. Genetic variation, beta-blockers, and perioperative myocardial infarction. Anesthesiology 2011;115:1316-27.

Nagele P, Meissner K, Francis A, Fodinger M, Saccone NL. Genetic and environmental determinants of plasma total homocysteine levels: impact of population-wide folate fortification. Pharmacogenet Genomics 2011;21:426-31.

Nagele P, Rao LK, Penta M, Kallogjeri D, Spitznagel EL, Cavallone LF, Nussenbaum B, Piccirillo JF. Postoperative myocardial injury after major head and neck cancer surgery. Head Neck 2011;33:1085-91.

Nagele P, Tallchief D, Blood J, Sharma A, Kharasch ED. Nitrous oxide anesthesia and plasma homocysteine in adolescents. Anesth Analg 2011;113:843-8.

Nissman KW, Nissman DB, Leighton BL, Varaday SS, Lockhart EM. Necrotizing fasciitis after cesarean delivery. Anesthesiology 2011;115:1301.

Noppers I, Olofsen E, Niesters M, Aarts L, Mooren R, Dahan A, Kharasch E, Sarton E. Effect of rifampicin on S-ketamine and S-norketamine plasma concentrations in healthy volunteers after intravenous S-ketamine administration. Anesthesiology 2011;114:1435-45.

Papadopoulos G, Karanikolas M, Liarmakopoulou A, Berris A. Baseline cerebral oximetry values in elderly patients with hip fractures: a prospective observational study. Injury 2011;42:1328-32.

Qiu CS, Lash-Van Wyhe L, Sasaki M, Sakai R, Swanson GT, Gereau RWt. Antinociceptive effects of MSVIII-19, a functional antagonist of the GluK1 kainate receptor. Pain 2011;152:1052-60.

Saifee O, Metz LB, Nonet ML, Crowder CM. A gain-of-function mutation in adenylate cyclase confers isoflurane resistance in Caenorhabditis elegans. Anesthesiology 2011;115:1162-71.

Schwedt TJ, Gereau RW, Frey K, Kharasch ED. Headache outcomes following treatment of unruptured intracranial aneurysms: a prospective analysis. Cephalalgia 2011;31:1082-9.

Schwedt TJ, Krauss MJ, Frey K, Gereau RWt. Episodic and chronic migraineurs are hypersensitive to thermal stimuli between migraine attacks. Cephalalgia 2011;31:6-12.

Selig HF, Trimmel H, Voelckel WG, Hupfl M, Trittenwein G, Nagele P. Prehospital pediatric emergencies in Austrian helicopter emergency medical service - a nationwide, population-based cohort study. Wien Klin Wochenschr 2011;123:552-8.

Sharkey AM, Sharma A. Tetralogy of Fallot: Anatomic Variants and Their Impact on Surgical Management. Semin Cardiothorac Vasc Anesth 2012.

Sharma A, Tallchief D, Blood J, Kim T, London A, Kharasch ED. Perioperative pharmacokinetics of methadone in adolescents. Anesthesiology 2011;115:1153-61.

Skrupky LP, Kerby PW, Hotchkiss RS. Advances in the management of sepsis and the understanding of key immunologic defects. Anesthesiology 2011;115:1349-62.

Spitzer D, Simon PO, Jr., Kashiwagi H, Xu J, Zeng C, Vangveravong S, Zhou D, Chang K, McDunn JE, Hornick JR, Goedegebuure P, Hotchkiss RS, Mach RH, Hawkins WG. Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling. Cancer Res 2012;72:201-9.

Stastna E, Krishnan K, Manion BD, Taylor A, Rath NP, Chen ZW, Evers AS, Zorumski CF, Mennerick S, Covey DF. Neurosteroid analogues. 16. A new explanation for the lack of anesthetic effects of delta(16)-alphaxalone and identification of a delta(17(20)) analogue with potent anesthetic activity. J Med Chem 2011;54:3926-34.

Steinbach JH. Flapping loops: roles for hinges in a ligand-binding domain of the nicotinic receptor. Mol Pharmacol 2011;79:337-9.

Steinbach JH, Akk G. Use of concatemers of ligand-gated ion channel subunits to study mechanisms of steroid potentiation. Anesthesiology 2011;115:1328-37.

Tivener D, Vannucci A, Fagley RE, Doyle M, Shenoy S, Chapman W, Kangrga I. Atrial laceration caused by removal of a transjugular intrahepatic portosystemic shunt necessitates emergent cardiopulmonary bypass during liver transplant: a case report. Transplant Proc 2011;43:2810-3.

Toma O, Suntrup P, Stefanescu A, London A, Mutch M, Kharasch E. Pharmacokinetics and tissue penetration of cefoxitin in obesity: implications for risk of surgical site infection. Anesth Analg 2011;113:730-7.

Vannucci A, Burykin A, Krejci V, Peck T, Buchman TG, Kangrga IM. Postreperfusion cardiac arrest and resuscitation during orthotopic liver transplantation: dynamic visualization and analysis of physiologic recordings. Shock 2012;37:34-8.

Vannucci A, Johnston J, Earl TM, Doyle M, Kangrga IM. Intraoperative transesophageal echocardiography guides liver transplant surgery in a patient with thrombosed transjugular intrahepatic portosystemic shunt. Anesthesiology 2011;115:1389-91.

Vannucci A, Tran LC, Kangrga IM. Inflammatory myofibroblastic tumor within intrahepatic inferior vena cava. Anesthesiology 2011;115:1299.

Viader A, Golden JP, Baloh RH, Schmidt RE, Hunter DA, Milbrandt J. Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function. J Neurosci 2011;31:10128-40.

Vretzakis G, Kleitsaki A, Aretha D, Karanikolas M. Management of intraoperative fluid balance and blood conservation techniques in adult cardiac surgery. Heart Surg Forum 2011;14:E28-39.

Werner J, Hartwig W, Hackert T, Kaiser H, Schmidt J, Gebhard MM, Buchler MW, Klar E. Multidrug strategies are effective in the treatment of severe experimental pancreatitis. Surgery 2011.

Whitlock EL, Vannucci A, Avidan MS. Postoperative delirium. Minerva Anestesiol 2011;77:448-56.

Whitlock EL, Villafranca AJ, Lin N, Palanca BJ, Jacobsohn E, Finkel KJ, Zhang L, Burnside BA, Kaiser HA, Evers AS, Avidan MS. Relationship between bispectral index values and volatile anesthetic concentrations during the maintenance phase of anesthesia in the B-Unaware trial. Anesthesiology 2011;115:1209-18.

Xu J, Zeng C, Chu W, Pan F, Rothfuss JM, Zhang F, Tu Z, Zhou D, Zeng D, Vangveravong S, Johnston F, Spitzer D, Chang KC, Hotchkiss RS, Hawkins WG, Wheeler KT, Mach RH. Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site. Nat Commun 2011;2:380.

Yang C, Zeng XH, Zhou Y, Xia XM, Lingle CJ. LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel. Proc Natl Acad Sci U S A 2011;108:19419-24.

Yi X, AuBuchon J, Zeltwanger S, Kirby JP. Necrotic arachnidism and intractable pain from recluse spider bites treated with lumbar sympathetic block: a case report and review of literature. Clin J Pain 2011;27:457-60.

Zammataro M, Chiechio S, Montana MC, Traficante A, Copani A, Nicoletti F, Gereau RWt. mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists. Mol Pain 2011;7:6.

Zeng C, Vangveravong S, Jones LA, Hyrc K, Chang KC, Xu J, Rothfuss JM, Goldberg MP, Hotchkiss RS, Mach RH. Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes. Mol Imaging 2011;10:420-33.

Zeng XH, Yang C, Kim ST, Lingle CJ, Xia XM. Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa. Proc Natl Acad Sci U S A 2011;108:5879-84.

Zhao C, Leitges M, Gereau RWt. Isozyme-specific effects of protein kinase C in pain modulation. Anesthesiology 2011;115:1261-70.

Zhou Y, Xia XM, Lingle CJ. Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region. Proc Natl Acad Sci U S A 2011;108:12161-6.