Department Publications 2010

Ahmed I, Rawat JD, Singh S, Sharma A, Pandey A, Goel M. Neurothekeoma: a rare sacrococcygeal tumor in a child. J Pediatr Surg 2010;45:1037-9.

Akk G. EDITORIAL: Molecular Pharmacology of the GABA(A) Receptor. Curr Neuropharmacol 2010;8:1.

Akk G, Covey DF, Evers AS, Mennerick S, Zorumski CF, Steinbach JH. Kinetic and Structural Determinants for GABA-A Receptor Potentiation by Neuroactive Steroids. Curr Neuropharmacol 2010;8:18-25.

Akk G, Li P, Bracamontes J, Wang M, Steinbach JH. Pharmacology of structural changes at the GABA(A) receptor transmitter binding site. Br J Pharmacol 2011;162:840-50.

Aleksic P, Bancevic V, Milovic N, Kosevic B, Stamenkovic DM, Karanikolas M, Campara ZM, Jovanovic M. Short ileal segment for orthotopic neobladder: a feasibility study. Int J Urol 2010;17:768-73.

Alter BJ, Zhao C, Karim F, Landreth GE, Gereau RWt. Genetic targeting of ERK1 suggests a predominant role for ERK2 in murine pain models. J Neurosci 2010;30:11537-47.

Apostolakis EE, Baikoussis NG, Kalogeropoulou C, Koletsis E, Koniari I, Karnabatidis D, Karanikolas M. Remnant of a non-patent ductus arteriosus mimicking traumatic thoracic aorta transection: a case report. J Cardiothorac Surg 2010;5:24.

Apostolakis EE, Baikoussis NG, Katsanos K, Karanikolas M. Postoperative peri-axillary seroma following axillary artery cannulation for surgical treatment of acute type A aortic dissection. J Cardiothorac Surg 2010;5:43.

Avidan MS, Xiong C, Evers AS. Postoperative cognitive decline: the unsubstantiated phenotype. Anesthesiology 2010;113:1246-8; author reply 8-50.

Baikoussis NG, Karanikolas M, Siminelakis S, Matsagas M, Papadopoulos G. Baseline cerebral oximetry values in cardiac and vascular surgery patients: a prospective observational study. J Cardiothorac Surg 2010;5:41.

Bandyopadhyaya AK, Manion BD, Benz A, Taylor A, Rath NP, Evers AS, Zorumski CF, Mennerick S, Covey DF. Neurosteroid analogues. 15. A comparative study of the anesthetic and GABAergic actions of alphaxalone, Delta16-alphaxalone and their corresponding 17-carbonitrile analogues. Bioorg Med Chem Lett 2010;20:6680-4.

Batista PA, Werner MF, Oliveira EC, Burgos L, Pereira P, Brum LF, Story GM, Santos AR. The antinociceptive effect of (-)-linalool in models of chronic inflammatory and neuropathic hypersensitivity in mice. J Pain 2010;11:1222-9.

Boulet JR, Murray DJ. Simulation-based assessment in anesthesiology: requirements for practical implementation. Anesthesiology 2010;112:1041-52.

Bradfute SB, Swanson PE, Smith MA, Watanabe E, McDunn JE, Hotchkiss RS, Bavari S. Mechanisms and consequences of ebolavirus-induced lymphocyte apoptosis. J Immunol 2010;184:327-35.

Brahmamdam P, Inoue S, Unsinger J, Chang KC, McDunn JE, Hotchkiss RS. Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis. J Leukoc Biol 2010;88:233-40.

Brambrink AM, Evers AS, Avidan MS, Farber NB, Smith DJ, Zhang X, Dissen GA, Creeley CE, Olney JW. Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain. Anesthesiology 2010;112:834-41.

Breshears JD, Roland JL, Sharma M, Gaona CM, Freudenburg ZV, Tempelhoff R, Avidan MS, Leuthardt EC. Stable and dynamic cortical electrophysiology of induction and emergence with propofol anesthesia. Proc Natl Acad Sci U S A 2010;107:21170-5.

Burykin A, Peck T, Krejci V, Vannucci A, Kangrga I, Buchman TG. Toward optimal display of physiologic status in critical care: I. Recreating bedside displays from archived physiologic data. J Crit Care 2010.

Cao YQ, Tsien RW. Different relationship of N- and P/Q-type Ca2+ channels to channel-interacting slots in controlling neurotransmission at cultured hippocampal synapses. J Neurosci 2010;30:4536-46.

Cattano D, Cavallone L. Airway Management and Patient Positioning: A Clinical Perspective. . Anesthesiology News 2010:35-40.

Cattano D, Altamirano A, Vannucci A, Melnikov V, Cone C, Hagberg CA. Preoperative use of incentive spirometry does not affect postoperative lung function in bariatric surgery. Transl Res 2010;156:265-72.

Chen B, Ge Q, Xia XM, Liu P, Wang SJ, Zhan H, Eipper BA, Wang ZW. A novel auxiliary subunit critical to BK channel function in Caenorhabditis elegans. J Neurosci 2010;30:16651-61.

Chiechio S, Copani A, Zammataro M, Battaglia G, Gereau RWt, Nicoletti F. Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain. Trends Pharmacol Sci 2010;31:153-60.

Chisari M, Shu HJ, Taylor A, Steinbach JH, Zorumski CF, Mennerick S. Structurally diverse amphiphiles exhibit biphasic modulation of GABAA receptors: similarities and differences with neurosteroid actions. Br J Pharmacol 2010;160:130-41.

Cooper JB, Murray D. Simulation training and assessment: a more efficient method to develop expertise than apprenticeship. Anesthesiology 2010;112:8-9.

Cox TE, Evers AS, Murray DJ. Leadership in postgraduate medical education. Anesthesiology 2010;113:754; author reply -5.

Culverhouse RC, Saccone NL, Stitzel JA, Wang JC, Steinbach JH, Goate AM, Schwantes-An TH, Grucza RA, Stevens VL, Bierut LJ. Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. Hum Genet 2011;129:177-88.

Dabrowska DM, Gore C, Griffiths S, Mudzingwa M, Varaday S. Anaesthetic management of a pregnant patient with multiple myeloma. Int J Obstet Anesth 2010;19:336-9.


Despotis GJ, Avidan MS. Plasma exchange for heparin-induced thrombocytopenia: is there enough evidence? Anesth Analg 2010;110:7-10.

Dilger JP, Steinbach JH. Inhibition of muscle acetylcholine receptors by nondepolarizing drugs: humans are not unique. Anesthesiology 2010;112:247-9; author reply 9-50.

Donados C, M. Karanikolas, P. Kaspis, A. Saridis, C. Matzaroglou. Monıtorıng Anaesthesıa Control Durıng Kyphoplastıes. The Internet Journal of Minimally Invasive Spinal Technology 2010;3.

Dooley J, Fingerman M, Melton S, Klein SM. Contralateral local anesthetic spread from an outpatient interscalene catheter. Can J Anaesth 2010;57:936-9.

Duncan JR, Katherine Henderson, Mandie Street, Amy Richmond, Mary Klingensmith, Elio Beta, Andrea Vannucci, David Murray. Creating and evaluating a data-driven curriculum for central venous catheter placement. Journal of Graduate Medical Education 2010;2:389-97.

Evers AS, Chen ZW, Manion BD, Han M, Jiang X, Darbandi-Tonkabon R, Kable T, Bracamontes J, Zorumski CF, Mennerick S, Steinbach JH, Covey DF. A synthetic 18-norsteroid distinguishes between two neuroactive steroid binding sites on GABAA receptors. J Pharmacol Exp Ther 2010;333:404-13.

Ezaru CS, Murray AW, Oravitz TM, Ibinson JW, Mangine MP. When ultrasound is not enough. J Ultrasound Med 2010;29:505; discussion 6-8.

Fan J, Meissner K, Gaehle GG, Li S, Kharasch ED, Mach RH, Tu Z. Automated radiosynthesis of [11C]morphine for clinical investigation. Appl Radiat Isot 2011;69:431-5.

Fehr J, Brockel M. Mucopolysaccharidoses. Essence of Anesthesia Practice 2010;3.

Fox AC, Robertson CM, Belt B, Clark AT, Chang KC, Leathersich AM, Dominguez JA, Perrone EE, Dunne WM, Hotchkiss RS, Buchman TG, Linehan DC, Coopersmith CM. Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis. Crit Care Med 2010;38:886-93.

Fuller B, Rivers, E. Should early goal directed therapy be the standard for sepsis? -pro: research supports it. Emergency Physicians Monthly 2010.

Garvin S, FitzGerald DC, Despotis G, Shekar P, Body SC. Heparin concentration-based anticoagulation for cardiac surgery fails to reliably predict heparin bolus dose requirements. Anesth Analg 2010;111:849-55.

Gazit AZ, Huddleston CB, Checchia PA, Fehr J, Pezzella AT. Care of the pediatric cardiac surgery patient--part 1. Curr Probl Surg 2010;47:185-250.

Gazit AZ, Huddleston CB, Checchia PA, Fehr J, Pezzella AT. Care of the pediatric cardiac surgery patient--part 2. Curr Probl Surg 2010;47:261-376.

Goepfert CE, Ifune C, Tempelhoff R. Ischemic optic neuropathy: are we any further? Curr Opin Anaesthesiol 2010;23:582-7.

Golden JP, Hoshi M, Nassar MA, Enomoto H, Wood JN, Milbrandt J, Gereau RWt, Johnson EM, Jr., Jain S. RET signaling is required for survival and normal function of nonpeptidergic nociceptors. J Neurosci 2010;30:3983-94.

Gupta A, Chandra N, Sharma A, Husain N, Kureel SN. Renal leiomyoma in a child: a rare renal tumor. J Pediatr Surg 2010;45:1900-3.

Holzki JF, Laschat M, Puder C. The pediatric larynx: a complicated organ. Anesth Analg 2010;110:1509-10; author reply 11.

Hupfl M, Selig HF, Nagele P. Chest-compression-only versus standard cardiopulmonary resuscitation: a meta-analysis. Lancet 2010;376:1552-7.

Inoue S, Unsinger J, Davis CG, Muenzer JT, Ferguson TA, Chang K, Osborne DF, Clark AT, Coopersmith CM, McDunn JE, Hotchkiss RS. IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis. J Immunol 2010;184:1401-9.

Jacobs B, Duncan JR, Street M, Murray D. Audio and video recording system for routine documentation of fluoroscopic procedures. J Vasc Interv Radiol 2010;21:725-9.

Joy MS, Frye RF, Stubbert K, Brouwer KR, Falk RJ, Kharasch ED. Use of enantiomeric bupropion and hydroxybupropion to assess CYP2B6 activity in glomerular kidney diseases. J Clin Pharmacol 2010;50:714-20.

Karanikolas M, Aretha D, Kiekkas P, Monantera G, Tsolakis I, Filos KS. Case report. Intravenous fentanyl patient-controlled analgesia for perioperative treatment of neuropathic/ischaemic pain in haemodialysis patients: a case series. J Clin Pharm Ther 2010;35:603-8.

Karanikolas M, Velissaris D, Marangos M, Karamouzos V, Fligou F, Filos KS. Prolonged high-dose intravenous magnesium therapy for severe tetanus in the intensive care unit: a case series. J Med Case Reports 2010;4:100.

Kasten KR, Prakash PS, Unsinger J, Goetzman HS, England LG, Cave CM, Seitz AP, Mazuski CN, Zhou TT, Morre M, Hotchkiss RS, Hildeman DA, Caldwell CC. Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis. Infect Immun 2010;78:4714-22.

Kertai MD, Pal N, Palanca BJ, Lin N, Searleman SA, Zhang L, Burnside BA, Finkel KJ, Avidan MS. Association of perioperative risk factors and cumulative duration of low bispectral index with intermediate-term mortality after cardiac surgery in the B-Unaware Trial. Anesthesiology 2010;112:1116-27.

Khanna P, Garg R, Sunder RA. Rosai-Dorfman disease--perianaesthetic concerns. Acta Anaesthesiol Belg 2010;61:1-3.

Kiekkas P, Karga M, Lemonidou C, Aretha D, Karanikolas M. Medication errors in critically ill adults: a review of direct observation evidence. Am J Crit Care 2011;20:36-44.

Kiekkas P, Velissaris D, Karanikolas M, Aretha D, Samios A, Skartsani C, Baltopoulos GI, Filos KS. Peak body temperature predicts mortality in critically ill patients without cerebral damage. Heart Lung 2010;39:208-16.

Kolber BJ, Montana MC, Carrasquillo Y, Xu J, Heinemann SF, Muglia LJ, Gereau RWt. Activation of metabotropic glutamate receptor 5 in the amygdala modulates pain-like behavior. J Neurosci 2010;30:8203-13.

Krejci V, Vannucci A, Abbas A, Chapman W, Kangrga IM. Comparison of calibrated and uncalibrated arterial pressure-based cardiac output monitors during orthotopic liver transplantation. Liver Transpl 2010;16:773-82.

Kuhn CM. The innovative anesthesiology curriculum: a challenge and hope for the future. Anesthesiology 2010;112:267-8.

Lagerstrom MC, Rogoz K, Abrahamsen B, Persson E, Reinius B, Nordenankar K, Olund C, Smith C, Mendez JA, Chen ZF, Wood JN, Wallen-Mackenzie A, Kullander K. VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch. Neuron 2010;68:529-42.

Lawrence KL, White PH, Morris GP, Jennemann J, Phelan DL, Hotchkiss RS, Kollef MH. CD4+ lymphocyte adenosine triphosphate determination in sepsis: a cohort study. Crit Care 2010;14:R110.

Lennerz JK, Hurov JB, White LS, Lewandowski KT, Prior JL, Planer GJ, Gereau RWt, Piwnica-Worms D, Schmidt RE, Piwnica-Worms H. Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis. Mol Cell Biol 2010;30:5043-56.

Li P, Khatri A, Bracamontes J, Weiss DS, Steinbach JH, Akk G. Site-specific fluorescence reveals distinct structural changes induced in the human rho 1 GABA receptor by inhibitory neurosteroids. Mol Pharmacol 2010;77:539-46.

Li P, Steinbach JH. The neuronal nicotinic alpha4beta2 receptor has a high maximal probability of being open. Br J Pharmacol 2010;160:1906-15.

Lobato RL, Despotis GJ, Levy JH, Shore-Lesserson LJ, Carlson MO, Bennett-Guerrero E. Anticoagulation management during cardiopulmonary bypass: a survey of 54 North American institutions. J Thorac Cardiovasc Surg 2010;139:1665-6.

Mao XR, Crowder CM. Protein misfolding induces hypoxic preconditioning via a subset of the unfolded protein response machinery. Mol Cell Biol 2010;30:5033-42.

Matzaroglou C, Bougas P, Panagiotopoulos E, Saridis A, Karanikolas M, Kouzoudis D. Ninety-degree chevron osteotomy for correction of hallux valgus deformity: clinical data and finite element analysis. Open Orthop J 2010;4:152-6.

Mazoit JX, Roulleau P, Baujard C. Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain: isoflurane or ischemia-reperfusion? Anesthesiology 2010;113:1245; author reply -6.

McConnell KW, McDunn JE, Clark AT, Dunne WM, Dixon DJ, Turnbull IR, Dipasco PJ, Osberghaus WF, Sherman B, Martin JR, Walter MJ, Cobb JP, Buchman TG, Hotchkiss RS, Coopersmith CM. Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct host responses. Crit Care Med 2010;38:223-41.

Meissner K, Ding M, Göpfert CE, Toma O, Buck N, Blood J, Kharasch ED. Variabilität von Wirkung und Nebenwirkungen von intravenösem Morphin und Hydromorphon zur postoperativen Schmerztherapie – eine Vergleichsstudie an gesunden Probanden (varaiability of effects and side effects of intravenous morphine and hydromorphone for postopertive pain therapy – a comparative study in healthy subjects). . DAC Nürnberg 2010.

Melby SJ, Larue SJ, Lasala JM, Pal N, Lakshminarasimhachar A, Trulock EP, Kreisel D, Pasque MK, Puri V, Patterson GA, Krupnick AS. Anatomic distortion of the right coronary artery as a complication of lung transplantation. Ann Thorac Surg 2010;89:2000-1.

Mizobuchi M, Nakamura H, Tokumoto M, Finch J, Morrissey J, Liapis H, Slatopolsky E. Myocardial effects of VDR activators in renal failure. J Steroid Biochem Mol Biol 2010;121:188-92.

Morrell MR, Despotis GJ, Lublin DM, Patterson GA, Trulock EP, Hachem RR. The efficacy of photopheresis for bronchiolitis obliterans syndrome after lung transplantation. J Heart Lung Transplant 2010;29:424-31.

Morrissey JJ, London AN, Luo J, Kharasch ED. Urinary biomarkers for the early diagnosis of kidney cancer. Mayo Clin Proc 2010;85:413-21.

Muenzer JT, Davis CG, Chang K, Schmidt RE, Dunne WM, Coopersmith CM, Hotchkiss RS. Characterization and modulation of the immunosuppressive phase of sepsis. Infect Immun 2010;78:1582-92.

Nagele P, Rao LK, Penta M, Kallogjeri D, Spitznagel EL, Cavallone LF, Nussenbaum B, Piccirillo JF. Postoperative myocardial injury after major head and neck cancer surgery. Head Neck 2010.

Nykiel S, Schrock CR, Murray DJ. Images in anesthesiology: transient paraplegia after anesthesia for magnetic resonance imaging. Anesthesiology 2010;113:687.

Pal N, Kertai MD, Lakshminarasimhachar A, Avidan MS. Pharmacology and clinical applications of human recombinant antithrombin. Expert Opin Biol Ther 2010;10:1155-68.

Papadopoulos G, Baikoussis NG, Tzimas P, Siminelakis SN, Karanikolas M. Intravenous levosimendan-norepinephrine combination during off-pump coronary artery bypass grafting in a hemodialysis patient with severe myocardial dysfunction. J Cardiothorac Surg 2010;5:9.

Pehbock D, Wenzel V, Voelckel W, Jonsson K, Herff H, Mittlbock M, Nagele P. Effects of preoxygenation on desaturation time during hemorrhagic shock in pigs. Anesthesiology 2010;113:593-9.

Rao LK, Francis AM, Wilcox U, Miller JP, Nagele P. Pre-operative vitamin B infusion and prevention of nitrous oxide-induced homocysteine increase. Anaesthesia 2010;65:710-5.

Rastogi R, Patel T, Swarm RA. Vertebral augmentation for compression fractures caused by malignant disease. J Natl Compr Canc Netw 2010;8:1095-102.

Saini DK, Gautam N. Live cell imaging for studying g protein-coupled receptor activation in single cells. Methods Mol Biol 2010;617:191-207.

Saini DK, Karunarathne WK, Angaswamy N, Saini D, Cho JH, Kalyanaraman V, Gautam N. Regulation of Golgi structure and secretion by receptor-induced G protein betagamma complex translocation. Proc Natl Acad Sci U S A 2010;107:11417-22.

Sanders RD, Avidan MS. Evidence is lacking for interventions proposed to prevent unintended awareness during general anesthesia for cesarean delivery. Anesth Analg 2010;110:972-3; author reply 3-4.

Scatizzi JC, Hutcheson J, Pope RM, Firestein GS, Koch AE, Mavers M, Smason A, Agrawal H, Haines GK, 3rd, Chandel NS, Hotchkiss RS, Perlman H. Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis. Arthritis Rheum 2010;62:441-51.

Silbert BS, Evered LA, Scott DA. Cognitive decline after surgery and illness. Anesthesiology 2010;112:1282; author reply 3-5.

Southard RE, Boyle WA. Corticosteroids and the original vasopressin and septic shock trial subgroups. Crit Care Med 2010;38:338; authore reply -9.

Spinos P, Matzaroglou C, Partheni M, Deli A, Karanikolas M, Konstantinou D. Surgical management of cervical spondyloarthropathy in hemodialysis patients. Open Orthop J 2010;4:39-43.

Spitzer D, McDunn JE, Plambeck-Suess S, Goedegebuure PS, Hotchkiss RS, Hawkins WG. A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing. Mol Cancer Ther 2010;9:2142-51.

Stock E, Vannucci A, Doyle M, Patterson GA, Chapman W, Kangrga I. Combined liver-kidney transplantation complicated by intraoperative discovery of a bronchobiliary fistula. Transplant Proc 2010;42:2800-3.

Swarm R, Abernethy AP, Anghelescu DL, Benedetti C, Blinderman CD, Boston B, Cleeland C, Coyle N, Deleon-Casasola OA, Eilers JG, Ferrell B, Janjan NA, Karver SB, Levy MH, Lynch M, Moryl N, Murphy BA, Nesbit SA, Oakes L, Obbens EA, Paice JA, Rabow MW, Syrjala KL, Urba S, Weinstein SM. Adult cancer pain. J Natl Compr Canc Netw 2010;8:1046-86.

Tang QY, Zhang Z, Xia XM, Lingle CJ. Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine. Channels (Austin) 2010;4:22-41.

Thors L, Burston JJ, Alter BJ, McKinney MK, Cravatt BF, Ross RA, Pertwee RG, Gereau RWt, Wiley JL, Fowler CJ. Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase. Br J Pharmacol 2010;160:549-60.

Unsinger J, Kazama H, McDonough JS, Griffith TS, Hotchkiss RS, Ferguson TA. Sepsis-induced apoptosis leads to active suppression of delayed-type hypersensitivity by CD8+ regulatory T cells through a TRAIL-dependent mechanism. J Immunol 2010;184:6766-72.

Unsinger J, McGlynn M, Kasten KR, Hoekzema AS, Watanabe E, Muenzer JT, McDonough JS, Tschoep J, Ferguson TA, McDunn JE, Morre M, Hildeman DA, Caldwell CC, Hotchkiss RS. IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis. J Immunol 2010;184:3768-79.

Vretzakis G, Kleitsaki A, Stamoulis K, Bareka M, Georgopoulou S, Karanikolas M, Giannoukas A. Intra-operative intravenous fluid restriction reduces perioperative red blood cell transfusion in elective cardiac surgery, especially in transfusion-prone patients: a prospective, randomized controlled trial. J Cardiothorac Surg 2010;5:7.

Xiang C, Zhang KH, Yin J, Arends JJ, Erzurumlu RS, Jacquin MF, Chen ZF. The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway. Mol Cell Neurosci 2010;44:394-403.

Zhou Y, Tang QY, Xia XM, Lingle CJ. Glycine311, a determinant of paxilline block in BK channels: a novel bend in the BK S6 helix. J Gen Physiol 2010;135:481-94.

Zhou Y, Xia X, Lingle CJ. Inhibition of large-conductance Ca2+-activated K+ channels by nanomolar concentrations of Ag+. Mol Pharmacol 2010;78:952-60.

Ziporin SJ, Ifune CK, MacConmara MP, Geraghty PJ, Choi ET. A case of external iliac arteriovenous fistula and high-output cardiac failure after endovenous laser treatment of great saphenous vein. J Vasc Surg 2010;51:715-9.