Department Publications 2009

Adesanya, A. O., E. Rosero, C. Wyrick, M. H. Wall and G. P. Joshi (2009). "Assessing the predictive value of the bispectral index vs patient state index on clinical assessment of sedation in postoperative cardiac surgery patients." J Crit Care 24(3): 322-8.

Akk, G., D. F. Covey, A. S. Evers, J. H. Steinbach, C. F. Zorumski and S. Mennerick (2009). "The influence of the membrane on neurosteroid actions at GABA(A) receptors." Psychoneuroendocrinology.

Akk, G., P. Li, J. Bracamontes and J. H. Steinbach (2009). "Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells." Molecular Pharmacology 75(6): 1400-11.

Anderson, L. L., X. Mao, B. A. Scott and C. M. Crowder (2009). "Survival from hypoxia in C. elegans by inactivation of aminoacyl-tRNA synthetases." Science 323(5914): 630-3.

Avidan, M. S., B. J. Palanca, D. Glick, E. Jacobsohn, A. Villafranca, M. O'Connor and G. A. Mashour (2009). "Protocol for the BAG-RECALL clinical trial: a prospective, multi-center, randomized, controlled trial to determine whether a bispectral index-guided protocol is superior to an anesthesia gas-guided protocol in reducing intraoperative awareness with explicit recall in high risk surgical patients." BMC Anesthesiol 9(1): 8.

Avidan, M. S., A. C. Searleman, M. Storandt, K. Barnett, A. Vannucci, L. Saager, C. Xiong, E. A. Grant, D. Kaiser, J. C. Morris and A. S. Evers (2009). "Long-term cognitive decline in older subjects was not attributable to noncardiac surgery or major illness." Anesthesiology 111(5): 964-70.

Bhatt, M., R. M. Kennedy, M. H. Osmond, B. Krauss, J. D. McAllister, J. M. Ansermino, L. M. Evered and M. G. Roback (2009). "Consensus-based recommendations for standardizing terminology and reporting adverse events for emergency department procedural sedation and analgesia in children." Ann Emerg Med 53(4): 426-435 e4.

Bracamontes, J. R. and J. H. Steinbach (2009). "Steroid interaction with a single potentiating site is sufficient to modulate GABA-A receptor function." Molecular Pharmacology 75(4): 973-81.

Brahmamdam, P., E. Watanabe, J. Unsinger, K. C. Chang, W. Schierding, A. S. Hoekzema, T. T. Zhou, J. S. McDonough, H. Holemon, J. D. Heidel, C. M. Coopersmith, J. E. McDunn and R. S. Hotchkiss (2009). "Targeted delivery of siRNA to cell death proteins in sepsis." Shock 32(2): 131-9.

Byrnes, M. C., D. J. Schuerer, M. E. Schallom, C. S. Sona, J. E. Mazuski, B. E. Taylor, W. McKenzie, J. M. Thomas, J. S. Emerson, J. L. Nemeth, R. A. Bailey, W. A. Boyle, T. G. Buchman and C. M. Coopersmith (2009). "Implementation of a mandatory checklist of protocols and objectives improves compliance with a wide range of evidence-based intensive care unit practices." Critical Care Medicine 37(10): 2775-81.

Cavallone, L. F. (2009). "Dreaming of patients' satisfaction." Minerva Anestesiol 75(6): 355-6.

Chen, R., C. A. Furman, M. Zhang, M. N. Kim, R. W. t. Gereau, M. Leitges and M. E. Gnegy (2009). "Protein kinase Cbeta is a critical regulator of dopamine transporter trafficking and regulates the behavioral response to amphetamine in mice." Journal of Pharmacology and Experimental Therapeutics 328(3): 912-20.

Chiechio, S., M. Zammataro, M. E. Morales, C. L. Busceti, F. Drago, R. W. t. Gereau, A. Copani and F. Nicoletti (2009). "Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain." Molecular Pharmacology 75(5): 1014-20.

Chisari, M., D. K. Saini, J. H. Cho, V. Kalyanaraman and N. Gautam (2009). "G protein subunit dissociation and translocation regulate cellular response to receptor stimulation." PLoS One 4(11): e7797.

Crawford, D. C., K. L. Moulder, R. W. t. Gereau, G. M. Story and S. Mennerick (2009). "Comparative effects of heterologous TRPV1 and TRPM8 expression in rat hippocampal neurons." PLoS One 4(12): e8166.

Crowder, C. M. (2009). "Cell biology. Ceramides--friend or foe in hypoxia?" Science 324(5925): 343-4.

Dalal, P. G., D. Murray, A. H. Messner, A. Feng, J. McAllister and D. Molter (2009). "Pediatric laryngeal dimensions: an age-based analysis." Anesthesia and Analgesia 108(5): 1475-9.

Despotis, G., M. Avidan and C. Eby (2009). "Prediction and management of bleeding in cardiac surgery." J Thromb Haemost 7 Suppl 1: 111-7.

Ellett, A. E., J. C. Shields, C. Ifune, N. Roa and A. Vannucci (2009). "A near miss: a nitrous oxide-carbon dioxide mix-up despite current safety standards." Anesthesiology 110(6): 1429-31.

Fagley, R. E., A. Woodbury, A. Visuara and M. Wall (2009). "Rocuronium-induced coronary vasospasm--"Kounis syndrome"." Int J Cardiol 137(2): e29-32.

Finkel, K. J., A. C. Searleman, H. Tymkew, C. Y. Tanaka, L. Saager, E. Safer-Zadeh, M. Bottros, J. A. Selvidge, E. Jacobsohn, D. Pulley, S. Duntley, C. Becker and M. S. Avidan (2009). "Prevalence of undiagnosed obstructive sleep apnea among adult surgical patients in an academic medical center." Sleep Med 10(7): 753-8.

Goudet, C., V. Magnaghi, M. Landry, F. Nagy, R. W. t. Gereau and J. P. Pin (2009). "Metabotropic receptors for glutamate and GABA in pain." Brain Res Rev 60(1): 43-56.

Hager, H., G. Mandadi, D. Pulley, J. C. Eagon, E. Mascha, B. Nutter and A. Kurz (2009). "A comparison of noninvasive blood pressure measurement on the wrist with invasive arterial blood pressure monitoring in patients undergoing bariatric surgery." Obes Surg 19(6): 717-24.

Hamouda, A. K., X. Jin, M. Sanghvi, S. Srivastava, A. Pandhare, P. K. Duddempudi, J. H. Steinbach and M. P. Blanton (2009). "Photoaffinity labeling the agonist binding domain of alpha4beta4 and alpha4beta2 neuronal nicotinic acetylcholine receptors with [(125)I]epibatidine and 5[(125)I]A-85380." Biochimica Et Biophysica Acta 1788(9): 1987-95.

Henrichs, B. M., M. S. Avidan, D. J. Murray, J. R. Boulet, J. Kras, B. Krause, R. Snider and A. S. Evers (2009). "Performance of certified registered nurse anesthetists and anesthesiologists in a simulation-based skills assessment." Anesthesia and Analgesia 108(1): 255-62.

Hotchkiss, R. S., C. M. Coopersmith, J. E. McDunn and T. A. Ferguson (2009). "The sepsis seesaw: tilting toward immunosuppression." Nature Medicine 15(5): 496-7.

Hotchkiss, R. S., A. Strasser, J. E. McDunn and P. E. Swanson (2009). "Cell death." New England Journal of Medicine 361(16): 1570-83.

Ji, R. R., R. W. t. Gereau, M. Malcangio and G. R. Strichartz (2009). "MAP kinase and pain." Brain Res Rev 60(1): 135-48.

Jin, X., D. F. Covey and J. H. Steinbach (2009). "Kinetic analysis of voltage-dependent potentiation and block of the glycine alpha 3 receptor by a neuroactive steroid analogue." Journal of Physiology 587(Pt 5): 981-97.

Jorgensen, H. F., Z. F. Chen, M. Merkenschlager and A. G. Fisher (2009). "Is REST required for ESC pluripotency?" Nature 457(7233): E4-5; discussion E7.

Jorgensen, H. F., A. Terry, C. Beretta, C. F. Pereira, M. Leleu, Z. F. Chen, C. Kelly, M. Merkenschlager and A. G. Fisher (2009). "REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells." Development 136(5): 715-21.

Kashiwagi, H., J. E. McDunn, P. O. Simon, Jr., P. S. Goedegebuure, S. Vangveravong, K. Chang, R. S. Hotchkiss, R. H. Mach and W. G. Hawkins (2009). "Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma." J Transl Med 7: 24.

Kertai, M. D., T. Tiszai-Szucs, K. S. Varga, C. Hermann, G. Acsady and J. Gal (2009). "Intraoperative use of packed red blood cell transfusion and mortality in patients undergoing abdominal or thoracoabdominal aortic aneurysm surgery." J Cardiovasc Surg (Torino) 50(4): 501-8.

Kharasch, E. D., C. Hoffer, D. Whittington, A. Walker and P. S. Bedynek (2009). "Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir." Anesthesiology 110(3): 660-72.

Kharasch, E. D., G. N. Subbarao, K. R. Cromack, D. A. Stephens and M. D. Saltarelli (2009). "Sevoflurane formulation water content influences degradation by Lewis acids in vaporizers." Anesthesia and Analgesia 108(6): 1796-802.

Kharasch, E. D., A. Walker, D. Whittington, C. Hoffer and P. S. Bedynek (2009). "Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity." Drug Alcohol Depend 101(3): 158-68.

Lanier, W. L. and E. D. Kharasch (2009). "Contemporary clinical opioid use: opportunities and challenges." Mayo Clin Proc 84(7): 572-5.

Li, P., A. K. Bandyopadhyaya, D. F. Covey, J. H. Steinbach and G. Akk (2009). "Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA(A) receptor is not obligatory for channel potentiation." Br J Pharmacol 158(5): 1322-9.

Li, Z. F., Z. D. Wang, Y. Y. Ji, S. Zhang, C. Huang, J. Li and X. M. Xia (2009). "Induction of apoptosis and cell cycle arrest in human HCC MHCC97H cells with Chrysanthemum indicum extract." World J Gastroenterol 15(36): 4538-46.

Li, Z. F., X. M. Xia, C. Huang, S. Zhang, J. Zhang and A. J. Zhang (2009). "Emodin and baicalein inhibit pancreatic stromal derived factor-1 expression in rats with acute pancreatitis." Hepatobiliary Pancreat Dis Int 8(2): 201-8.

Liu, Q., Z. Tang, L. Surdenikova, S. Kim, K. N. Patel, A. Kim, F. Ru, Y. Guan, H. J. Weng, Y. Geng, B. J. Undem, M. Kollarik, Z. F. Chen, D. J. Anderson and X. Dong (2009). "Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus." Cell 139(7): 1353-65.

Mabon, M. E., X. Mao, Y. Jiao, B. A. Scott and C. M. Crowder (2009). "Systematic identification of gene activities promoting hypoxic death." Genetics 181(2): 483-96.

Mabon, M. E., B. A. Scott and C. M. Crowder (2009). "Divergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/insulin/IGF-receptor pathway." PLoS One 4(11): e7937.

Mashour, G. A., R. K. Esaki, K. K. Tremper, D. B. Glick, M. O'Connor and M. S. Avidan (2009). "A Novel Classification Instrument for Intraoperative Awareness Events." Anesthesia and Analgesia.

Mashour, G. A., K. K. Tremper and M. S. Avidan (2009). "Protocol for the "Michigan Awareness Control Study": A prospective, randomized, controlled trial comparing electronic alerts based on bispectral index monitoring or minimum alveolar concentration for the prevention of intraoperative awareness." BMC Anesthesiol 9: 7.

McDunn, J. E. and R. S. Hotchkiss (2009). "Leukocyte phenotyping to stratify septic shock patients." Crit Care 13(2): 127.

McDunn, J. E., J. T. Muenzer, B. Dunne, A. Zhou, K. Yuan, A. Hoekzema, C. Hilliard, K. C. Chang, C. G. Davis, J. McDonough, C. Hunt, P. Grigsby, D. Piwnica-Worms and R. S. Hotchkiss (2009). "An anti-apoptotic peptide improves survival in lethal total body irradiation." Biochemical and Biophysical Research Communications 382(4): 657-62.

Montana, M. C., L. F. Cavallone, K. K. Stubbert, A. D. Stefanescu, E. D. Kharasch and R. W. t. Gereau (2009). "The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine." Journal of Pharmacology and Experimental Therapeutics 330(3): 834-43.

Morales, M. E. and R. W. Gereau (2009). "The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli." PLoS One 4(7): e6457.

Nagele, P., B. Zeugswetter, C. Eberle, M. Hupfl, M. Mittlbock and M. Fodinger (2009). "A common gene variant in methionine synthase reductase is not associated with peak homocysteine concentrations after nitrous oxide anesthesia." Pharmacogenet Genomics 19(5): 325-9.

Okazaki, M., S. Sugimoto, J. Lai, C. G. Kornfeld, R. S. Hotchkiss, S. B. Richardson, W. Li, F. H. Kreisel, H. J. Huang, G. A. Patterson, A. S. Krupnick, A. E. Gelman and D. Kreisel (2009). "Costimulatory blockade-mediated lung allograft acceptance is abrogated by overexpression of Bcl-2 in the recipient." Transplant Proc 41(1): 385-7.

Pal, N. and R. Mehra (2009). "Unusual right atrium indentation: poststernum closure." Journal of Cardiothoracic and Vascular Anesthesia 23(5): 751-2.

Palanca, B. J., G. A. Mashour and M. S. Avidan (2009). "Processed electroencephalogram in depth of anesthesia monitoring." Current Opinion in Anaesthesiology 22(5): 553-9.

Parsons, A. J. and J. Alfa (2009). "Carotid dissection: a complication of internal jugular vein cannulation with the use of ultrasound." Anesthesia and Analgesia 109(1): 135-6.

Peck-Palmer, O. M., J. Unsinger, K. C. Chang, J. S. McDonough, H. Perlman, J. E. McDunn and R. S. Hotchkiss (2009). "Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages." Shock 31(4): 359-66.

Pickrell, J. E., K. Hosaka, D. L. Jackson, M. Heima, E. Kharasch and P. M. Milgrom (2009). "Expanded studies of the pharmacokinetics and clinical effects of multidose sublingual triazolam in healthy volunteers." J Clin Psychopharmacol 29(5): 426-31.

Racz, K., T. Tiszai-Szucs, J. Gal and D. M. Kertai (2009). "[Preoperative revascularization in high-risk patients undergoing vascular surgery]." Orv Hetil 150(8): 341-52.

Saccone, N. L., J. C. Wang, N. Breslau, E. O. Johnson, D. Hatsukami, S. F. Saccone, R. A. Grucza, L. Sun, W. Duan, J. Budde, R. C. Culverhouse, L. Fox, A. L. Hinrichs, J. H. Steinbach, M. Wu, J. P. Rice, A. M.Goate and L. J. Bierut (2009). "The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans." Cancer Res 69(17): 6848-56.

Saini, D. K., M. Chisari and N. Gautam (2009). "Shuttling and translocation of heterotrimeric G proteins and Ras." Trends Pharmacol Sci 30(6): 278-86.

Scherrer, G., N. Imamachi, Y. Q. Cao, C. Contet, F. Mennicken, D. O'Donnell, B. L. Kieffer and A. I. Basbaum (2009). "Dissociation of the opioid receptor mechanisms that control mechanical and heat pain." Cell 137(6): 1148-59.

Shu, H. J., L. N. Eisenman, C. Wang, A. K. Bandyopadhyaya, K. Krishnan, A. Taylor, A. M. Benz, B. Manion, A. S. Evers, D. F. Covey, C. F. Zorumski and S. Mennerick (2009). "Photodynamic effects of steroid-conjugated fluorophores on GABAA receptors." Molecular Pharmacology 76(4): 754-65.

Simon, P. O., Jr., J. E. McDunn, H. Kashiwagi, K. Chang, P. S. Goedegebuure, R. S. Hotchkiss and W. G. Hawkins (2009). "Targeting AKT with the proapoptotic peptide, TAT-CTMP: a novel strategy for the treatment of human pancreatic adenocarcinoma." Int J Cancer 125(4): 942-51.

Sona, C. S., J. E. Zack, M. E. Schallom, M. McSweeney, K. McMullen, J. Thomas, C. M. Coopersmith, W. A. Boyle, T. G. Buchman, J. E. Mazuski and D. J. Schuerer (2009). "The impact of a simple, low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensive care unit." Journal of Intensive Care Medicine 24(1): 54-62.

Stromberg, P. E., C. A. Woolsey, A. T. Clark, J. A. Clark, I. R. Turnbull, K. W. McConnell, K. C. Chang, C. S. Chung, A. Ayala, T. G. Buchman, R. S. Hotchkiss and C. M. Coopersmith (2009). "CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis." Faseb J 23(6): 1817-25.

Stucky, C. L., A. E. Dubin, N. A. Jeske, S. A. Malin, D. D. McKemy and G. M. Story (2009). "Roles of transient receptor potential channels in pain." Brain Res Rev 60(1): 2-23.

Sun, L., Y. Xiong, X. Zeng, Y. Wu, N. Pan, C. J. Lingle, A. Qu and J. Ding (2009). "Differential regulation of action potentials by inactivating and noninactivating BK channels in rat adrenal chromaffin cells." Biophysical Journal 97(7): 1832-42.

Sun, Y. G., N. G. Gracias, J. K. Drobish, M. R. Vasko, R. W. Gereau and Z. F. Chen (2009). "The c-kit signaling pathway is involved in the development of persistent pain." Pain 144(1-2): 178-86.

Sun, Y. G., Z. Q. Zhao, X. L. Meng, J. Yin, X. Y. Liu and Z. F. Chen (2009). "Cellular basis of itch sensation." Science 325(5947): 1531-4.

Tang, Q. Y., X. H. Zeng and C. J. Lingle (2009). "Closed-channel block of BK potassium channels by bbTBA requires partial activation." Journal of General Physiology 134(5): 409-36.

Turnbull, I. R., A. T. Clark, P. E. Stromberg, D. J. Dixon, C. A. Woolsey, C. G. Davis, R. S. Hotchkiss, T. G. Buchman and C. M. Coopersmith (2009). "Effects of aging on the immunopathologic response to sepsis." Critical Care Medicine 37(3): 1018-23.

Unsinger, J., H. Kazama, J. S. McDonough, R. S. Hotchkiss and T. A. Ferguson (2009). "Differential lymphopenia-induced homeostatic proliferation for CD4+ and CD8+ T cells following septic injury." J Leukoc Biol 85(3): 382-90.

Unsinger, J., J. S. McDonough, L. D. Shultz, T. A. Ferguson and R. S. Hotchkiss (2009). "Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice." J Leukoc Biol 86(2): 219-27.

Vannucci, A., V. Krejci and I. Kangrga (2009). "Performance of Vigileo and LiDCOplus cardiac output monitors during a prolonged cardiac arrest and resuscitation." Eur J Anaesthesiol 26(10): 885-7.

Vannucci, A., V. Krejci and I. Kangrga (2009). "Validation of a new cardiac output monitor." Liver Transpl 15(11): 1650; author reply 1651-2.

Waldrop, W. B., D. J. Murray, J. R. Boulet and J. F. Kras (2009). "Management of anesthesia equipment failure: a simulation-based resident skill assessment." Anesthesia and Analgesia 109(2): 426-33.

Wang, J. C., C. Cruchaga, N. L. Saccone, S. Bertelsen, P. Liu, J. P. Budde, W. Duan, L. Fox, R. A. Grucza, J. Kern, K. Mayo, O. Reyes, J. Rice, S. F. Saccone, N. Spiegel, J. H. Steinbach, J. A. Stitzel, M. W. Anderson, M. You, V. L. Stevens, L. J. Bierut and A. M. Goate (2009). "Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5." Hum Mol Genet 18(16): 3125-35.

Watanabe, E., J. T. Muenzer, W. G. Hawkins, C. G. Davis, D. J. Dixon, J. E. McDunn, D. J. Brackett, M. R. Lerner, P. E. Swanson and R. S. Hotchkiss (2009). "Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study." Lab Invest 89(5): 549-61.

Yang, C. T., X. H. Zeng, X. M. Xia and C. J. Lingle (2009). "Interactions between beta subunits of the KCNMB family and Slo3: beta4 selectively modulates Slo3 expression and function." PLoS One 4(7): e6135.

Zhang, Z., X. H. Zeng, X. M. Xia and C. J. Lingle (2009). "N-terminal inactivation domains of beta subunits are protected from trypsin digestion by binding within the antechamber of BK channels." Journal of General Physiology 133(3): 263-82.