Department Publications 2005

Akk, G., L. S. Milescu, et al. (2005). "Activation of heteroliganded mouse muscle nicotinic receptors." J Physiol 564(Pt 2): 359-76.

Akk, G. and J. H. Steinbach (2005). "Galantamine activates muscle-type nicotinic acetylcholine receptors without binding to the acetylcholine-binding site." J Neurosci 25(8): 1992-2001.

Akk, G., H. J. Shu, et al. (2005). "Neurosteroid access to the GABAA receptor." J Neurosci 25(50): 11605-13.

Alagarsamy, S., J. Saugstad, et al. (2005). "NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin." Neuropharmacology 49 Suppl 1: 135-45.

Avidan, M. S., J. H. Levy, et al. (2005). "Recombinant human antithrombin III restores heparin responsiveness and decreases activation of coagulation in heparin-resistant patients during cardiopulmonary bypass." J Thorac Cardiovasc Surg 130(1): 107-13.

Avidan, M. S., J. H. Levy, et al. (2005). "A phase III, double-blind, placebo-controlled, multicenter study on the efficacy of recombinant human antithrombin in heparin-resistant patients scheduled to undergo cardiac surgery necessitating cardiopulmonary bypass." Anesthesiology 102(2): 276-84.

Azpiazu, I., M. Akgoz, et al. (2005). "G protein betagamma11 complex translocation is induced by Gi, Gq and Gs coupling receptors and is regulated by the alpha subunit type." Cell Signal.

Chaobal, H. N. and E. D. Kharasch (2005). "Single-point sampling for assessment of constitutive, induced, and inhibited cytochrome P450 3A activity with alfentanil or midazolam." Clin Pharmacol Ther 78(5): 529-39.

Checchia, P. A., J. McCollegan, et al. (2005). "The effect of surgical case volume on outcome after the Norwood procedure." J Thorac Cardiovasc Surg 129(4): 754-9.

Chen, X. K., L. C. Wang, et al. (2005). "Activation of GPCRs modulates quantal size in chromaffin cells through G(betagamma) and PKC." Nat Neurosci 8(9): 1160-8.

Cohen, M. S., S. E. Finkelstein, et al. (2005). "Outpatient minimally invasive parathyroidectomy using local/regional anesthesia: a safe and effective operative approach for selected patients." Surgery 138(4): 681-7; discussion 687-9.

D'Angelo, R., B. Philip, et al. (2005). "A randomized, double-blind, close-ranging, pilot study of intravenous granisetron in the prevention of postoperative nausea and vomiting in patients abdominal hysterectomy." Eur J Anaesthesiol 22(10): 774-9.

Degler, S. M., R. D. Dowling, et al. (2005). "Awake intubation using an intubating laryngeal mask airway in a parturient with spina bifida." Int J Obstet Anesth 14(1): 77-8.

Dembo, G., S. B. Park, et al. (2005). "Central nervous system concentrations of cyclooxygenase-2 inhibitors in humans." Anesthesiology 102(2): 409-15.

Despotis, G., M. Avidan, et al. (2005). "Off-label use of recombinant factor VIIA concentrates after cardiac surgery." Ann Thorac Surg 80(1): 3-5.

Ding, Y. Q., J. Y. Kim, et al. (2005). "Ventral migration of early-born neurons requires Dcc and is essential for the projections of primary afferents in the spinal cord." Development 132(9): 2047-56.

Ding, Y. Q., C. X. Xiang, et al. (2005). "Generation and characterization of the PKCgamma-Cre mouse line." Genesis 43(1): 28-33.

Dunston, J. A., T. Reimschisel, et al. (2005). "A neurological phenotype in nail patella syndrome (NPS) patients illuminated by studies of murine Lmx1b expression." Eur J Hum Genet 13(3): 330-5.

Faury, G., T. M. Wynnychenko, et al. (2005). "Decreased circulating elastin peptide levels in humans with sepsis." Pathol Biol (Paris) 53(7): 443-7.

Gereau, R. W. t. (2005). "Neurofibromatosis pain is in the membrane. Focus on "sensory neurons from Nf1 haploinsufficient mice exhibit increased excitability"." J Neurophysiol 94(6): 3659-60.

Guarino, A. H. and N. Wright (2005). "Pneumocephalus: a case study." Pain Physician 8: 239-241.

Guarino, A. H. and M. Cornell (2005). "Opioids as an option in MS patients with chronic pain." International Journal of MS Care 7(1): 10-15.

Hidaka, T., I. Tsuneyoshi, et al. (2005). "Marked synergism between vasopressin and angiotensin II in a human isolated artery." Crit Care Med 33(11): 2613-20.

Hogue, C. W., Jr., L. L. Creswell, et al. (2005). "Epidemiology, mechanisms, and risks: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery." Chest 128(2 Suppl): 9S-16S.

Hooten, W. M., M. Karanikolas, et al. (2005). "Postoperative pain management following bilateral lung volume reduction surgery for severe emphysema." Anaesth Intensive Care 33(5): 591-6.

Hotchkiss, R. S., S. B. Osmon, et al. (2005). "Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways." J Immunol 174(8): 5110-8.

Hupfl, M., A. Duma, et al. (2005). "Over-the-head cardiopulmonary resuscitation improves efficacy in basic life support performed by professional medical personnel with a single rescuer: a simulation study." Anesth Analg 101(1): 200-5, table of contents.

Jacobsohn, E., T. W. Lee, et al. (2005). "Low-dose intrathecal morphine does not delay early extubation after cardiac surgery." Can J Anaesth 52(8): 848-57.

Jacobsohn, E., C. De Wet, et al. (2005). "Use of the Patient State Index (PSI) to assist in the diagnosis of perioperative neurological injury and brain death." J Clin Monit Comput 19(3): 219-22.

Javadi, P., T. G. Buchman, et al. (2005). "Iron dysregulation combined with aging prevents sepsis-induced apoptosis." J Surg Res 128(1): 37-44.

Kailasam, R., C. A. Palin, et al. (2005). "Atrial fibrillation after cardiac surgery: an evidence-based approach to prevention." Semin Cardiothorac Vasc Anesth 9(1): 77-85.

Kharasch, E. D., A. Walker, et al. (2005). "Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination." J Clin Pharmacol 45(1): 79-88.

Kharasch, E. D., D. Whittington, et al. (2005). "Paradoxical role of cytochrome P450 3A in the bioactivation and clinical effects of levo-alpha-acetylmethadol: importance of clinical investigations to validate in vitro drug metabolism studies." Clin Pharmacokinet 44(7): 731-51.

Kharasch, E. D., A. Walker, et al. (2005). "Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity." J Clin Pharmacol 45(10): 1187-97.

Kharasch, E. D., K. E. Thummel, et al. (2005). "CYP3A Probes Can Quantitatively Predict the In Vivo Kinetics of Other CYP3A Substrates and Can Accurately Assess CYP3A Induction and Inhibition." Mol Interv 5(3): 151-3.

Kharasch, E. D., J. L. Schroeder, et al. (2005). "Influence of sevoflurane on the metabolism and renal effects of compound A in rats." Anesthesiology 103(6): 1183-8.

Klees, T. M., P. Sheffels, et al. (2005). "Pharmacogenetic determinants of human liver microsomal alfentanil metabolism and the role of cytochrome P450 3A5." Anesthesiology 102(3): 550-6.

Klees, T. M., P. Sheffels, et al. (2005). "Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes." Drug Metab Dispos 33(3): 303-11.

Leone, M., A. Charvet, et al. (2005). "Terlipressin: a new therapeutic for calcium-channel blockers overdose." J Crit Care 20(1): 114-115.

McDonald, S. B., M. Renna, et al. (2005). "Preoperative use of enoxaparin increases the risk of postoperative bleeding and re-exploration in cardiac surgery patients." J Cardiothorac Vasc Anesth 19(1): 4-10.

McDonald, S. B., E. Jacobsohn, et al. (2005). "Parasternal block and local anesthetic infiltration with levobupivacaine after cardiac surgery with desflurane: the effect on postoperative pain, pulmonary function, and tracheal extubation times." Anesth Analg 100(1): 25-32.

Milescu, L. S., G. Akk, et al. (2005). "Maximum likelihood estimation of ion channel kinetics from macroscopic currents." Biophys J 88(4): 2494-515.

Murray, D. J., J. R. Boulet, et al. (2005). "A simulation-based acute skills performance assessment for anesthesia training." Anesth Analg 101(4): 1127-34, table of contents.

Murray, D. (2005). "Clinical simulation: measuring the efficacy of training." Curr Opin Anaesthesiol 18(6): 645-8.

Nagele, P., J. B. Mendel, et al. (2005). "Volatile Anesthetics Bind Rat Synaptic Snare Proteins." Anesthesiology 103(4): 768-778.

Nast, P. A., M. Avidan, et al. (2005). "Reporting and classification of patient safety events in a cardiothoracic intensive care unit and cardiothoracic postoperative care unit." J Thorac Cardiovasc Surg 130(4): 1137.

Schreiber, T. and W. Boyle (2005). "Lung injury caused by mechanical ventilation." Contemporary Critical Care 3(6): 1-11.

Stanko, L. K., E. Jacobsohn, et al. (2005). "Transthoracic echocardiography: impact on diagnosis and management in tertiary care intensive care units." Anaesth Intensive Care 33(4): 492-6.

Textoris, J., M. Leone, et al. (2005). "[Selective digestive decontamination: the light as changed from red to green]." Ann Fr Anesth Reanim 24(4): 366-76.

Willson, D. F., N. J. Thomas, et al. (2005). "Effect of exogenous surfactant (calfactant) in pediatric acute lung injury: a randomized controlled trial." Jama 293(4): 470-6.

Yi, X., A. J. Cook, et al. (2005). "Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis?" J Pain 6(10): 700-3.

Zeng, X. H., X. M. Xia, et al. (2005). "Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites." J Gen Physiol 125(3): 273-86.

Zeng, C. M., B. D. Manion, et al. (2005). "Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one." J Med Chem 48(8): 3051-9.